Application of molecular orbital theory to elucidation of radical processes induced by radiation damage to DNA. The calculation of relative binding thermodynamics of molecular associations in aqueous environments. Classification-based molecular sequence analysis D. States, W. Reisdorf, Jr. Computational gene prediction using neural networks and similarity search Y.

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Explore a preview version of Developing Bioinformatics Computer Skills right now. Bioinformatics--the application of computational and analytical methods to biological problems--is a rapidly evolving scientific discipline. Genome sequencing projects are producing vast amounts of biological data for many different organisms, and, increasingly, storing these data in public databases.

Such biological databases are growing exponentially, along with the biological literature. It's impossible for even the most zealous researcher to stay on top of necessary information in the field without the aid of computer-based tools. Bioinformatics is all about building these tools.

Developing Bioinformatics Computer Skills is for scientists and students who are learning computational approaches to biology for the first time, as well as for experienced biology researchers who are just starting to use computers to handle their data. The book covers the Unix file system, building tools and databases for bioinformatics, computational approaches to biological problems, an introduction to Perl for bioinformatics, data mining, and data visualization.

Written in a clear, engaging style, Developing Bioinformatics Computer Skills will help biologists develop a structured approach to biological data as well as the tools they'll need to analyze the data. Skip to main content.

Start your free trial. Book Description Bioinformatics--the application of computational and analytical methods to biological problems--is a rapidly evolving scientific discipline. Show and hide more. Table of Contents Product Information. Introduction 1. Biology in the Computer Age 1. How Is Computing Changing Biology?

The Eye of the Fly 1. Labels in Gene Sequences 1. The First Information Age in Biology 1. What Does Informatics Mean to Biologists? What Skills Should a Bioinformatician Have? Why Should Biologists Use Computers? A New Approach to Data Collection 1. Why Use Unix or Linux? What Information and Software Are Available?

What Questions Can Bioinformatics Answer? Computational Approaches to Biological Questions 2. Molecular Biology's Central Dogma 2. Replication of DNA 2. Genomes and Genes 2. Transcription of DNA 2. Translation of mRNA 2. Molecular Evolution 2. What Biologists Model 2. Abstractions for Modeling Protein Structure 2. Mathematical Modeling of Biochemical Systems 2.

Why Biologists Model 2. Computational Methods Covered in This Book 2. A Computational Biology Experiment 2. Identifying the Problem 2. Separating the Problem into Simpler Components 2. Evaluating Your Needs 2. Selecting the Appropriate Data Set 2. Identifying the Criteria for Success 2. Performing and Documenting a Computational Experiment 2. Documentation issues in computational biology 2.

Electronic notebooks II. The Bioinformatics Workstation 3. Setting Up Your Workstation 3. Working on a Unix System 3. What Does an Operating System Do? Why Use Unix? Different Flavors of Unix 3. Linux 3.

Will Linux run on your computer? Other common flavors 3. Graphical Interfaces for Unix 3. Setting Up a Linux Workstation 3. Installing Linux 3. System requirements 3. Partitioning your disk 3. Selecting major package groupings 3. Other useful packages to add 3. How to Get Software Working 3. Unix tar Archives 3. Binary Distributions 3. RPM Archives 3. GnoRPM 3. Source Distributions 3. Perl Scripts 3.

Putting It in Your Path 3. Sharing Software Among Multiple Users 3. What Software Is Needed? Files and Directories in Unix 4. Filesystem Basics 4. Moving Around the Directory Hierarchy 4. Paths to Files and Directories 4.

Using a Process-Based File Hierarchy 4. Structuring a Project: An Example 4. Commands for Working with Directories and Files 4. Moving Around the Filesystem 4. You are here: pwd 4. Changing directories with cd 4. Finding Files and Directories 4. Listing files with ls 4. Interpreting ls output 4. Finding files with find 4. Finding an executable file with which 4. Finding an executable file with whereis 4. Manipulating Files and Directories 4. Copying files and directories with cp 4. Moving and renaming files and directories with mv 4.

Creating new links to files and directories with ln 4. Creating and removing directories with mkdir and rmdir 4. Removing files with rm 4. Working in a Multiuser Environment 4. Users and Groups 4. User Directories 4.


Developing Bioinformatics Computer Skills









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